April 7th
2:15 PM
Introductory remarks
2:30-4:00 PM
Type I Diabetes/Immunology [Basic]
Chair; Quizi Tang, PhD
Todd Brusko, PhD (Bluestone lab)
Development of Engineered Antigen-specific Human Regulatory T Cells for the Treatment of Type 1 Diabetes by TCR Gene Transfer
Tony Shum, MD (Anderson lab)
The Aire knockout mouse as a model for lung specific autoimmunity
Rachel Friedman, PhD (Krummel lab)
Sustained T cell-DC interactions in the islets induce DC maturation
Hans Dooms, PhD (Abbas Lab)
STAT5 and Tregs
Ashley Martin (Tang lab)
Regulatory T cell modulation of dendritic cells in the control of autoimmune diabetes
Josh Beilke, PhD (Lanier Lab)
Analysis of NK cells in the NOD pancreas
4:00- 4:30 PM
Coffee Break
4:30-6:00 PM
Central regulation of Energy Homeostasis
Chair: Allison Xu, PhD
Jamila Newton, PhD (Xu Lab)
Why do we get fatter as we get older?
Jacqueline Siljee, PhD (Vaisse Lab)
Primary cilia and obesity: What role does the melanocortin 4 receptor play?
Clement Cheung, MD, PhD (Ingraham Lab)
What's all the "fez" about a novel transcriptional factor in VMH development?
Shi-Bing Yang, PhD (Jan Lab)
mTOR signaling in POMC neurons causes obesity via activating KATP channel
Supriya Srinivasan, PhD (Ashrafi lab)
Serotonergic mechanisms of energy balance in C. elegans
6:00-7:00PM
Dinner
7:00-8:30 PM
Poster Session with (healthy) Desserts/Drinks
8:30 PM
Skits/Games…etc…
April 8th
7:00-8:30 AM
Breakfast
8:30-10:30 AM
Adipocyte/Peripheral Metabolism/Inflammation
Chairs: Suneil Koliwad, MD PhD /Jack Youngren, PhD
Greg Ku, MD PhD (McManus Lab)
Whole genome RNAi screen for novel regulators of the insulin promoter in beta cells
Stephane Vassilopoulos, PhD (Brodsky lab)
A role for clathrin CHC22 in human glucose metabolism
Charlie Harris, MD PhD (Farese Lab)
Grappling with Glucocorticoids and Metabolic Disease
Eva Herker, PhD (Ott Lab)
Diacylglycerol Acyltransferase 1 is a Novel Host Factor for Hepatitis C Virus Replication
Songcan Chen, MD (Gardner Lab)
Deletion of vitamin D receptor in cardiomyocytes causes cardiac hypertrophy
Carlos Pantoja, MD (Yamamoto lab)
Glucocorticoid Signaling Defines a Novel Commitment State During Adipogenesis In Vitro
Amnon Schlegel, MD PhD (Stainier Lab)
An unbiased molecular genetic approach to studying hepatic metabolism
10:30-10:45 AM
Coffee Break
10:45-12:00 PM
Epidemiology and Intervention in Type I and Type 2 diabetes
Chairs: Alka Kanaya, MD / Steve Gitelman, MD
Madhu Rao, MD (Morrie Schambelan’s group)
The effects of IGF-1/IGFBP-3 treatment on glucose metabolism and fat distribution in HIV infected men with insulin resistance and abdominal obesity
Dean Schillinger, MD
Literacy and Type 2 Diabetes
Alka Kanaya, MD
South Asians: A Unique Diabetes Phenotype
Andrew Posselt, MD PhD
Islet Allograft Survival in Type 1 Diabetics Using a Calcineurin Inhibitor-free Protocol Based on Efalizumab
Barbara Laraia, MD PhD RD
Results from the DISTANCE study.
12:00-1:00 PM
Lunch
1:00-2:20 PM
Free time
Joint Session Diabetes Center/IRM
2:20 PM
Preservation and regeneration of pancreas and liver function
Chair: Eric Rulifson, PhD
2:20-2:40 Jeff Bluestone, PhD
The present and future of diabetes research at UCSF
2:40-2:50 Eric Rulifson, PhD
Specification of the endocrine axis in Drosophila
2:50-3:05 Helen Hwang (Rulifson lab)
Choosing the insulin-producing cell progenitor from a placodal
equivalence group
3:05-3:15 Didier Stainier, MD
Beta Cell Differentiation in Zebrafish
3:15-3:30 Ryan Anderson, PhD (Stainier lab)
Beta Cell Regeneration in Zebrafish
3:30-3:40 Feroz Papa, PhD
ER stress signaling in the beta-cell
3:40-3:55 Phil Merksamer (Papa lab)
Lighting up the stressed ER with redox-responsive reporters
3:55-4:30 BREAK
4:30-4:40 Miguel Ramalho-Santos, PhD
Regulation of embryonic stem cell pluripotency and reprogramming
4:40-4:55 Alexandre Gaspar Maia (Ramalho-Santos lab)
Linking open chromatin to pluripotency
4:55-5:05 Holger Willenbring, MD
Overcoming roadblocks in stem cell-based therapies of liver diseases
5:05-5:20 Amar Deep Sharma, MD (Willenbring lab)
MicroRNAs: Novel regulators of liver function
5:20-5:30 Matthias Hebrok, PhD
5:30-5:45 John Morris (Hebrok lab)
Probing acinar plasticity in regeneration and disease
5:45-6:00 Stuart Smith, PhD (German lab)
RFX6 is essential for normal islet development in mice and humans
6:00-7:00 PM
Dinner
7:00-8:00 PM
Keynote speaker: Alan Trounson, PhD
President of the California Institute for Regenerative Medicine in
San Francisco, California
8:00-10:00 PM
IRM poster session
